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Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression

BACKGROUND: PGRMC1 (progesterone receptor membrane component 1) is a highly conserved heme binding protein, which is overexpressed especially in hormone receptor-positive breast cancer and plays an important role in breast carcinogenesis. Nevertheless, little is known about the mechanisms by which P...

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Detalles Bibliográficos
Autores principales: Asperger, Hannah, Stamm, Nadia, Gierke, Berthold, Pawlak, Michael, Hofmann, Ute, Zanger, Ulrich M., Marton, Annamaria, Katona, Robert L., Buhala, Andrea, Vizler, Csaba, Cieslik, Jan-Philipp, Ruckhäberle, Eugen, Niederacher, Dieter, Fehm, Tanja, Neubauer, Hans, Ludescher, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359014/
https://www.ncbi.nlm.nih.gov/pubmed/32660617
http://dx.doi.org/10.1186/s13058-020-01312-8