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IMMUNEPOTENT CRP induces DAMPS release and ROS-dependent autophagosome formation in HeLa and MCF-7 cells

BACKGROUND: IMMUNEPOTENT CRP (ICRP) can be cytotoxic to cancer cell lines. However, its widespread use in cancer patients has been limited by the absence of conclusive data on the molecular mechanism of its action. Here, we evaluated the mechanism of cell death induced by ICRP in HeLa and MCF-7 cell...

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Detalles Bibliográficos
Autores principales: Martínez-Torres, Ana Carolina, Reyes-Ruiz, Alejandra, Calvillo-Rodriguez, Kenny Misael, Alvarez-Valadez, Karla Maria, Uscanga-Palomeque, Ashanti C., Tamez-Guerra, Reyes S., Rodríguez-Padilla, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359018/
https://www.ncbi.nlm.nih.gov/pubmed/32660440
http://dx.doi.org/10.1186/s12885-020-07124-5