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Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal

[Image: see text] A hallmark of human immunodeficiency type-1 (HIV) infection is the integration of the viral genome into host chromatin, resulting in a latent reservoir that persists despite antiviral therapy or immune response. Thus, key priorities toward eradication of HIV infection are to unders...

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Detalles Bibliográficos
Autores principales: Turner, Anne-Marie W., Dronamraju, Raghuvar, Potjewyd, Frances, James, Katherine S., Winecoff, Daniel K., Kirchherr, Jennifer L., Archin, Nancie M., Browne, Edward P., Strahl, Brian D., Margolis, David M., James, Lindsey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359025/
https://www.ncbi.nlm.nih.gov/pubmed/32347704
http://dx.doi.org/10.1021/acsinfecdis.9b00514