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Acetylation dependent functions of Rab22a-NeoF1 Fusion Protein in Osteosarcoma
Background: Rab22a-NeoF1 fusion gene containing the 1-38aa of Rab22a (Rab22a(1-38)) plays a decisive role in driving tumor metastasis by activating RhoA via binding to SmgGDS607. However, its intercellular regulation remains unknown. Methods: The Lys7 (K7) acetylation of Rab22a-NeoF1 was initially i...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359080/ https://www.ncbi.nlm.nih.gov/pubmed/32685017 http://dx.doi.org/10.7150/thno.46082 |