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Neuronal RNA‐binding protein dysfunction in multiple sclerosis cortex

OBJECTIVE: Neurodegeneration is thought to be the primary cause of neurological disability in multiple sclerosis (MS). Dysfunctional RNA‐binding proteins (RBPs) including their mislocalization from nucleus to cytoplasm, stress granule formation, and altered RNA metabolism have been found to underlie...

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Detalles Bibliográficos
Autores principales: Salapa, Hannah E., Hutchinson, Catherine, Popescu, Bogdan F., Levin, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359129/
https://www.ncbi.nlm.nih.gov/pubmed/32608162
http://dx.doi.org/10.1002/acn3.51103