Evaluating the Incidence of Opioid-Induced Respiratory Depression Associated with Oliceridine and Morphine as Measured by the Frequency and Average Cumulative Duration of Dosing Interruption in Patients Treated for Acute Postoperative Pain

BACKGROUND AND OBJECTIVE: Opioid-induced respiratory depression (OIRD) is a potentially fatal complication associated with conventional opioids. Currently, there is a paucity of validated endpoints available to measure respiratory safety. Oliceridine, an investigational intravenous (IV) opioid, is a...

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Detalles Bibliográficos
Autores principales: Ayad, Sabry, Demitrack, Mark A., Burt, David A., Michalsky, Cathy, Wase, Linda, Fossler, Michael J., Khanna, Ashish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359152/
https://www.ncbi.nlm.nih.gov/pubmed/32583295
http://dx.doi.org/10.1007/s40261-020-00936-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359152/
https://www.ncbi.nlm.nih.gov/pubmed/32583295
http://dx.doi.org/10.1007/s40261-020-00936-0

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