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Evaluation of the Potential Pharmacokinetic Interactions Between Vixotrigine and an Oral Contraceptive

BACKGROUND AND OBJECTIVE: Vixotrigine is a voltage- and use-dependent sodium channel blocker in development for neuropathic pain management. This study evaluated the effect of coadministration of vixotrigine (metabolized primarily via uridine diphosphate-glucuronosyltransferases) and an oral contrac...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan, Versavel, Mark, Tidemann-Miller, Beth, Christmann, Romy, Naik, Himanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359159/
https://www.ncbi.nlm.nih.gov/pubmed/32564301
http://dx.doi.org/10.1007/s40261-020-00931-5