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Evaluation of the Potential Pharmacokinetic Interactions Between Vixotrigine and an Oral Contraceptive
BACKGROUND AND OBJECTIVE: Vixotrigine is a voltage- and use-dependent sodium channel blocker in development for neuropathic pain management. This study evaluated the effect of coadministration of vixotrigine (metabolized primarily via uridine diphosphate-glucuronosyltransferases) and an oral contrac...
Autores principales: | Zhao, Yuan, Versavel, Mark, Tidemann-Miller, Beth, Christmann, Romy, Naik, Himanshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359159/ https://www.ncbi.nlm.nih.gov/pubmed/32564301 http://dx.doi.org/10.1007/s40261-020-00931-5 |
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