Radiobiological and dosimetric assessment of DNA-intercalated (99m)Tc-complexes bearing acridine orange derivatives

BACKGROUND: Recently, a new family of (99m)Tc(I)-tricarbonyl complexes bearing an acridine orange (AO) DNA targeting unit and different linkers between the Auger emitter ((99m)Tc) and the AO moiety was evaluated for Auger therapy. Among them, (99m)Tc-C(3) places the corresponding radionuclide at a s...

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Detalles Bibliográficos
Autores principales: Belchior, Ana, Di Maria, Salvatore, Fernandes, Célia, Vaz, Pedro, Paulo, António, Raposinho, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359215/
https://www.ncbi.nlm.nih.gov/pubmed/32661612
http://dx.doi.org/10.1186/s13550-020-00663-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359215/
https://www.ncbi.nlm.nih.gov/pubmed/32661612
http://dx.doi.org/10.1186/s13550-020-00663-9

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