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Radiobiological and dosimetric assessment of DNA-intercalated (99m)Tc-complexes bearing acridine orange derivatives
BACKGROUND: Recently, a new family of (99m)Tc(I)-tricarbonyl complexes bearing an acridine orange (AO) DNA targeting unit and different linkers between the Auger emitter ((99m)Tc) and the AO moiety was evaluated for Auger therapy. Among them, (99m)Tc-C(3) places the corresponding radionuclide at a s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359215/ https://www.ncbi.nlm.nih.gov/pubmed/32661612 http://dx.doi.org/10.1186/s13550-020-00663-9 |