Deciphering cellular transcriptional alterations in Alzheimer’s disease brains

Large-scale brain bulk-RNAseq studies identified molecular pathways implicated in Alzheimer’s disease (AD), however these findings can be confounded by cellular composition changes in bulk-tissue. To identify cell intrinsic gene expression alterations of individual cell types, we designed a bioinfor...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Allen, Mariet, Li, Shaoyu, Quicksall, Zachary S., Patel, Tulsi A., Carnwath, Troy P., Reddy, Joseph S., Carrasquillo, Minerva M., Lincoln, Sarah J., Nguyen, Thuy T., Malphrus, Kimberly G., Dickson, Dennis W., Crook, Julia E., Asmann, Yan W., Ertekin-Taner, Nilüfer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359236/
https://www.ncbi.nlm.nih.gov/pubmed/32660529
http://dx.doi.org/10.1186/s13024-020-00392-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359236/
https://www.ncbi.nlm.nih.gov/pubmed/32660529
http://dx.doi.org/10.1186/s13024-020-00392-6

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