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Immunohistochemical detection of p53 and pp53 Ser(392) in canine hemangiomas and hemangiosarcomas located in the skin
BACKGROUND: p53 protein is essential for the regulation of cell proliferation. Aberrant accumulation of it usually occurs in cutaneous malignancies. Mutant p53 is detected by immunohistochemistry because it is more stable than the wild-type p53. However, post-translational modifications of p53 in re...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359283/ https://www.ncbi.nlm.nih.gov/pubmed/32660487 http://dx.doi.org/10.1186/s12917-020-02457-6 |