Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis

Women with intrahepatic cholestasis of pregnancy (ICP), a disorder characterised by raised serum bile acids, are at increased risk of developing gestational diabetes mellitus and have impaired glucose tolerance whilst cholestatic. FXR and TGR5 are modulators of glucose metabolism, and FXR activity i...

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Detalles Bibliográficos
Autores principales: Bellafante, Elena, McIlvride, Saraid, Nikolova, Vanya, Fan, Hei Man, Manna, Luiza Borges, Chambers, Jenny, Machirori, Mavis, Banerjee, Anita, Murphy, Kevin, Martineau, Marcus, Schoonjans, Kristina, Marschall, Hanns-Ulrich, Jones, Peter, Williamson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359298/
https://www.ncbi.nlm.nih.gov/pubmed/32661285
http://dx.doi.org/10.1038/s41598-020-67968-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359298/
https://www.ncbi.nlm.nih.gov/pubmed/32661285
http://dx.doi.org/10.1038/s41598-020-67968-6

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