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Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission

Cellular processes are inherently noisy, and the selection for accurate responses in presence of noise has likely shaped signalling networks. Here, we investigate the trade-off between accuracy of information transmission and its energetic cost for a mitogen-activated protein kinase (MAPK) signallin...

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Detalles Bibliográficos
Autores principales: Anders, Alexander, Ghosh, Bhaswar, Glatter, Timo, Sourjik, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359329/
https://www.ncbi.nlm.nih.gov/pubmed/32661402
http://dx.doi.org/10.1038/s41467-020-17276-4