In vitro treatment of 3 T3-L1 adipocytes with recombinant Calcium/calmodulin-dependent Protein Kinase IV (CaMKIV) limits ER stress and improves insulin sensitivity through inhibition of autophagy via the mTOR/CREB signaling pathway

BACKGROUND: Recently, CaMKIV has been identified as a potential regulator of skeletal muscle glucose metabolism, it can also affect insulin gene expression in pancreas. However, its effects on adipose insulin resistance have yet to be explored. Autophagy has been shown as a potential therapeutic tar...

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Detalles Bibliográficos
Autores principales: Liu, Jiali, Yang, Ruihua, Meng, Hao, Zhou, Ting, He, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359471/
https://www.ncbi.nlm.nih.gov/pubmed/32660483
http://dx.doi.org/10.1186/s12902-020-00589-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359471/
https://www.ncbi.nlm.nih.gov/pubmed/32660483
http://dx.doi.org/10.1186/s12902-020-00589-2

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