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Down-regulation of FTX promotes the differentiation of osteoclasts in osteoporosis through the Notch1 signaling pathway by targeting miR-137

BACKGROUND: Osteoporosis (OP) is one of the commonly seen bone diseases with low bone mineral densities and trauma fractures. Accumulative studies have demonstrated that the occurrence of OP is closely related to osteoclasts differentiation. LncRNA FTX has been demonstrated to inhibit the developmen...

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Detalles Bibliográficos
Autores principales: Yu, Yingfeng, Yao, Peiquan, Wang, Zhikun, Xie, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359489/
https://www.ncbi.nlm.nih.gov/pubmed/32660465
http://dx.doi.org/10.1186/s12891-020-03458-0