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Human B cell clonal expansion and convergent antibody responses to SARS CoV-2

During virus infection B cells are critical for the production of antibodies and protective immunity. Here we show that the human B cell compartment in patients with diagnostically confirmed SARS-CoV-2 and clinical COVID-19 is rapidly altered with the early recruitment of B cells expressing a limite...

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Detalles Bibliográficos
Autores principales: Nielsen, Sandra C. A., Yang, Fan, Jackson, Katherine J. L., Hoh, Ramona A., Röltgen, Katharina, Stevens, Bryan, Lee, Ji-Yeun, Rustagi, Arjun, Rogers, Angela J., Powell, Abigail E., Najeeb, Javaria, Otrelo-Cardoso, Ana R., Yost, Kathryn E., Daniel, Bence, Chang, Howard Y., Satpathy, Ansuman T., Jardetzky, Theodore S., Kim, Peter S., Wang, Taia T., Pinsky, Benjamin A., Blish, Catherine A., Boyd, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359515/
https://www.ncbi.nlm.nih.gov/pubmed/32676593
http://dx.doi.org/10.1101/2020.07.08.194456