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Comprehensive in-vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

SARS-CoV-2 is the positive-sense RNA virus that causes COVID-19, a disease that has triggered a major human health and economic crisis. The genome of SARS-CoV-2 is unique among viral RNAs in its vast potential to form stable RNA structures and yet, as much as 97% of its 30 kilobases have not been st...

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Detalles Bibliográficos
Autores principales: Huston, Nicholas C., Wan, Han, de Cesaris Araujo Tavares, Rafael, Wilen, Craig, Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359520/
https://www.ncbi.nlm.nih.gov/pubmed/32676598
http://dx.doi.org/10.1101/2020.07.10.197079