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The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis

BACKGROUND: Dysregulation of the host immune response is a pathognomonic feature of sepsis. Abnormal physiological conditions are understood to shift efficient linear splicing of protein-coding RNA towards non-canonical splicing, characterized by the accumulation of non-coding circularized (circ)RNA...

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Detalles Bibliográficos
Autores principales: Khan, Hina N., Brands, Xanthe, Aufiero, Simona, Hoogendijk, Arie J., Klarenbeek, Augustijn M., van Engelen, Tjitske S. R., Haak, Bastiaan W., van Vught, Lonneke A., Horn, Janneke, Schultz, Marcus J., Zwinderman, Aeilko H., van der Poll, Tom, Scicluna, Brendon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359566/
https://www.ncbi.nlm.nih.gov/pubmed/32660590
http://dx.doi.org/10.1186/s13054-020-03146-4