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The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis
BACKGROUND: Dysregulation of the host immune response is a pathognomonic feature of sepsis. Abnormal physiological conditions are understood to shift efficient linear splicing of protein-coding RNA towards non-canonical splicing, characterized by the accumulation of non-coding circularized (circ)RNA...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359566/ https://www.ncbi.nlm.nih.gov/pubmed/32660590 http://dx.doi.org/10.1186/s13054-020-03146-4 |