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The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis
BACKGROUND: Dysregulation of the host immune response is a pathognomonic feature of sepsis. Abnormal physiological conditions are understood to shift efficient linear splicing of protein-coding RNA towards non-canonical splicing, characterized by the accumulation of non-coding circularized (circ)RNA...
Autores principales: | Khan, Hina N., Brands, Xanthe, Aufiero, Simona, Hoogendijk, Arie J., Klarenbeek, Augustijn M., van Engelen, Tjitske S. R., Haak, Bastiaan W., van Vught, Lonneke A., Horn, Janneke, Schultz, Marcus J., Zwinderman, Aeilko H., van der Poll, Tom, Scicluna, Brendon P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359566/ https://www.ncbi.nlm.nih.gov/pubmed/32660590 http://dx.doi.org/10.1186/s13054-020-03146-4 |
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