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Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments

Endolysosomal compartments maintain cellular fitness by clearing dysfunctional organelles and proteins from cells. Modulation of their activity offers therapeutic opportunities. Quantification of cargo delivery to and/or accumulation within endolysosomes is instrumental for characterizing lysosome-d...

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Detalles Bibliográficos
Autores principales: Morone, Diego, Marazza, Alessandro, Bergmann, Timothy J., Molinari, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359569/
https://www.ncbi.nlm.nih.gov/pubmed/32401604
http://dx.doi.org/10.1091/mbc.E20-04-0269