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Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments
Endolysosomal compartments maintain cellular fitness by clearing dysfunctional organelles and proteins from cells. Modulation of their activity offers therapeutic opportunities. Quantification of cargo delivery to and/or accumulation within endolysosomes is instrumental for characterizing lysosome-d...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359569/ https://www.ncbi.nlm.nih.gov/pubmed/32401604 http://dx.doi.org/10.1091/mbc.E20-04-0269 |