The Hec1/Ndc80 tail domain is required for force generation at kinetochores, but is dispensable for kinetochore–microtubule attachment formation and Ska complex recruitment

The conserved kinetochore-associated NDC80 complex (composed of Hec1/Ndc80, Nuf2, Spc24, and Spc25) has well-documented roles in mitosis including 1) connecting mitotic chromosomes to spindle microtubules to establish force-transducing kinetochore–microtubule attachments and 2) regulating the bindin...

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Detalles Bibliográficos
Autores principales: Wimbish, Robert T., DeLuca, Keith F., Mick, Jeanne E., Himes, Jack, Jiménez-Sánchez, Ignacio, Jeyaprakash, A. Arockia, DeLuca, Jennifer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359571/
https://www.ncbi.nlm.nih.gov/pubmed/32401635
http://dx.doi.org/10.1091/mbc.E20-05-0286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359571/
https://www.ncbi.nlm.nih.gov/pubmed/32401635
http://dx.doi.org/10.1091/mbc.E20-05-0286

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