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Mitochondria regulate intestinal stem cell proliferation and epithelial homeostasis through FOXO

A metabolic transition from glycolysis to oxidative phosphorylation is often associated with differentiation of many types of stem cells. However, the link between mitochondrial respiration and stem cells’ behavior is not fully understood. We genetically disrupted electron transport chain (ETC) comp...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Pirooznia, Mehdi, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359575/
https://www.ncbi.nlm.nih.gov/pubmed/32374658
http://dx.doi.org/10.1091/mbc.E19-10-0560