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FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling

BACKGROUND: The formation of supernumerary teeth is an excellent model for studying the molecular mechanisms that control stem/progenitor cell homeostasis needed to generate a renewable source of replacement cells and tissues. Although multiple growth factors and transcriptional factors have been as...

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Detalles Bibliográficos
Autores principales: Wu, Jingyi, Tian, Ye, Han, Lu, Liu, Chao, Sun, Tianyu, Li, Ling, Yu, Yanlei, Lamichhane, Bikash, D’Souza, Rena N., Millar, Sarah E., Krumlauf, Robb, Ornitz, David M., Feng, Jian Q., Klein, Ophir, Zhao, Hu, Zhang, Fuming, Linhardt, Robert J., Wang, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359594/
https://www.ncbi.nlm.nih.gov/pubmed/32664967
http://dx.doi.org/10.1186/s12915-020-00813-4