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CSF total tau/α-synuclein ratio improved the diagnostic performance for Alzheimer’s disease as an indicator of tau phosphorylation

BACKGROUND: Recently, several studies suggested potential involvements of α-synuclein in Alzheimer’s disease (AD) pathophysiology. Higher concentrations of α-synuclein were reported in cerebrospinal fluid (CSF) of AD patients with a positive correlation towards CSF tau, indicating its possible role...

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Detalles Bibliográficos
Autores principales: Shim, Kyu Hwan, Kang, Min Ju, Suh, Jee Won, Pyun, Jung-Min, Ryoo, Nayoung, Park, Young Ho, Youn, Young Chul, Jang, Jae-Won, Jeong, Jee Hyang, Park, Kyung Won, Choi, Seong Hye, Suk, Kyoungho, Lee, Ho-Won, Ko, Pan-Woo, Lee, Chan-Nyoung, Lim, Tae-Sung, An, Seong Soo A., Kim, SangYun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359621/
https://www.ncbi.nlm.nih.gov/pubmed/32660565
http://dx.doi.org/10.1186/s13195-020-00648-9