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miR-214-3p Attenuates Sepsis-Induced Myocardial Dysfunction in Mice by Inhibiting Autophagy through PTEN/AKT/mTOR Pathway

Aims. More than half of the patients with sepsis would develop cardiac dysfunction, which is termed as sepsis-induced myocardial dysfunction (SIMD). Previous studies suggest that autophagy may play an important role in SIMD. The present study investigated whether miR-214-3p could attenuate SIMD by i...

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Detalles Bibliográficos
Autores principales: Sang, Zhenzhen, Zhang, Pu, Wei, Yunxia, Dong, Shimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359738/
https://www.ncbi.nlm.nih.gov/pubmed/32714974
http://dx.doi.org/10.1155/2020/1409038