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Systems Analysis of Insulin and IGF1 Receptors Networks in Breast Cancer Cells Identifies Commonalities and Divergences in Expression Patterns

Insulin and insulin-like growth factor-1 (IGF1), acting respectively via the insulin (INSR) and IGF1 (IGF1R) receptors, play key developmental and metabolic roles throughout life. In addition, both signaling pathways fulfill important roles in cancer initiation and progression. The present study was...

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Detalles Bibliográficos
Autores principales: Sarfstein, Rive, Yeheskel, Adva, Sinai-Livne, Tali, Pasmanik-Chor, Metsada, Werner, Haim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359857/
https://www.ncbi.nlm.nih.gov/pubmed/32733384
http://dx.doi.org/10.3389/fendo.2020.00435