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Nano-Encapsulation of Coenzyme Q10 in Secondary and Tertiary Nano-Emulsions for Enhanced Cardioprotection and Hepatoprotection in Human Cardiomyocytes and Hepatocytes During Exposure to Anthracyclines and Trastuzumab

INTRODUCTION: CoenzymeQ(10) (CoQ(10)) is a well-known antioxidant and anti-inflammatory agent with cardioprotective properties. However, clinical trials based on its oral administration have failed to provide significant effect on cardiac functionality. The main limitation of CoQ(10) is based on its...

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Detalles Bibliográficos
Autores principales: Quagliariello, Vincenzo, Vecchione, Raffaele, De Capua, Alberta, Lagreca, Elena, Iaffaioli, Rosario Vincenzo, Botti, Gerardo, Netti, Paolo A, Maurea, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359894/
https://www.ncbi.nlm.nih.gov/pubmed/32764923
http://dx.doi.org/10.2147/IJN.S245170