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Restoring the Platelet miR-223 by Calpain Inhibition Alleviates the Neointimal Hyperplasia in Diabetes

Platelet hyperactivity is the hallmark of diabetes, and platelet activation plays a crucial role in diabetic vascular complications. Recent studies have shown that upon activation, platelet-derived miRNAs are incorporated into vascular smooth muscle cells (VSMCs), regulating the phenotypic switch of...

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Detalles Bibliográficos
Autores principales: Su, Meiling, Fan, Shunyang, Ling, Zhenwei, Fan, Xuejiao, Xia, Luoxing, Liu, Yingying, Li, Shaoying, Zhang, Yuan, Zeng, Zhi, Tang, Wai Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359912/
https://www.ncbi.nlm.nih.gov/pubmed/32733269
http://dx.doi.org/10.3389/fphys.2020.00742