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A Simple and Rapid UPLC‐UV Method for Detecting DPD Deficiency in Patients With Cancer

Detecting patients with dihydropyrimidine dehydrogenase (DPD) deficiency is becoming a major concern in clinical oncology. Monitoring physiologic plasma uracil and/or plasma uracil‐to‐dihydrouracil metabolic ratio is a common surrogate frequently used to determine DPD phenotype without direct measur...

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Detalles Bibliográficos
Autores principales: Marin, Clémence, Krache, Anis, Palmaro, Chloé, Lucas, Mathilde, Hilaire, Valentin, Ugdonne, Renée, De Victor, Bénédicte, Quaranta, Sylvie, Solas, Caroline, Lacarelle, Bruno, Ciccolini, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359930/
https://www.ncbi.nlm.nih.gov/pubmed/32058656
http://dx.doi.org/10.1111/cts.12762