Impact of Vancomycin‐Induced Changes in the Intestinal Microbiota on the Pharmacokinetics of Simvastatin

The pharmacokinetic (PK) properties of drugs are affected in several ways by interactions with microbiota. The aim of this study was to investigate the effects of oral vancomycin on the gut microbiota and, consequently, on the PKs of simvastatin. An open‐label, single arm, sequential crossover study...

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Detalles Bibliográficos
Autores principales: Sunwoo, Jung, Ji, Sang Chun, Kim, Andrew HyoungJin, Yu, Kyung‐Sang, Cho, Joo‐Youn, Jang, In‐Jin, Lee, SeungHwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359932/
https://www.ncbi.nlm.nih.gov/pubmed/32058642
http://dx.doi.org/10.1111/cts.12761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359932/
https://www.ncbi.nlm.nih.gov/pubmed/32058642
http://dx.doi.org/10.1111/cts.12761

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