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Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand (11)C-UCB-J

ABSTRACT: The ability to quantify synaptic density in vivo in human adults and adolescents is of vital importance to understanding neuropsychiatric disorders. Here, we performed whole-body scans to determine organ radiation dosimetry of (11)C-UCB-J in humans. METHODS: Dynamic whole-body PET scans we...

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Detalles Bibliográficos
Autores principales: Bini, Jason, Holden, Daniel, Fontaine, Kathryn, Mulnix, Tim, Lu, Yihuan, Matuskey, David, Ropchan, Jim, Nabulsi, Nabeel, Huang, Yiyun, Carson, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359974/
https://www.ncbi.nlm.nih.gov/pubmed/32666239
http://dx.doi.org/10.1186/s13550-020-00670-w