Cargando…
Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand (11)C-UCB-J
ABSTRACT: The ability to quantify synaptic density in vivo in human adults and adolescents is of vital importance to understanding neuropsychiatric disorders. Here, we performed whole-body scans to determine organ radiation dosimetry of (11)C-UCB-J in humans. METHODS: Dynamic whole-body PET scans we...
Autores principales: | Bini, Jason, Holden, Daniel, Fontaine, Kathryn, Mulnix, Tim, Lu, Yihuan, Matuskey, David, Ropchan, Jim, Nabulsi, Nabeel, Huang, Yiyun, Carson, Richard E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359974/ https://www.ncbi.nlm.nih.gov/pubmed/32666239 http://dx.doi.org/10.1186/s13550-020-00670-w |
Ejemplares similares
-
Feasibility of imaging synaptic density in the human spinal cord using [(11)C]UCB-J PET
por: Rossano, Samantha, et al.
Publicado: (2022) -
Human biodistribution and dosimetry of [(11)C]-UCB-J, a PET radiotracer for imaging synaptic density
por: Cawthorne, Christopher, et al.
Publicado: (2021) -
Association of Aβ deposition and regional synaptic density in early Alzheimer’s disease: a PET imaging study with [(11)C]UCB-J
por: O’Dell, Ryan S., et al.
Publicado: (2021) -
Principal component analysis of synaptic density measured with [(11)C]UCB-J PET in early Alzheimer’s disease
por: O'Dell, Ryan S., et al.
Publicado: (2023) -
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [(11)C]UCB‐J
por: Mecca, Adam P., et al.
Publicado: (2022)