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Acute Promyelocytic Leukemia: A History over 60 Years—From the Most Malignant to the most Curable Form of Acute Leukemia
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) that is cytogenetically characterized by a balanced reciprocal translocation between chromosomes 15 and 17, which results in the fusion of the promyelocytic leukemia (PML) and retinoic acid receptor alpha (RARα)...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Healthcare
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360001/ https://www.ncbi.nlm.nih.gov/pubmed/32700196 http://dx.doi.org/10.1007/s40487-018-0091-5 |