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Head-to-head comparisons of Toxoplasma gondii and its near relative Hammondia hammondi reveal dramatic differences in the host response and effectors with species-specific functions

Toxoplasma gondii and Hammondia hammondi are closely-related coccidian intracellular parasites that differ in their ability to cause disease in animal and (likely) humans. The role of the host response in these phenotypic differences is not known and to address this we performed a transcriptomic ana...

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Detalles Bibliográficos
Autores principales: Wong, Zhee Sheen, Sokol-Borrelli, Sarah L., Olias, Philip, Dubey, J. P., Boyle, Jon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360062/
https://www.ncbi.nlm.nih.gov/pubmed/32574210
http://dx.doi.org/10.1371/journal.ppat.1008528