Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication

Homologous recombination (HR) has an intimate relationship with genome replication, both during repair of DNA lesions that might prevent DNA synthesis and in tackling stalls to the replication fork. Recent studies led us to ask if HR might have a more central role in replicating the genome of Leishm...

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Detalles Bibliográficos
Autores principales: Damasceno, Jeziel D., Reis-Cunha, João, Crouch, Kathryn, Beraldi, Dario, Lapsley, Craig, Tosi, Luiz R. O., Bartholomeu, Daniella, McCulloch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360064/
https://www.ncbi.nlm.nih.gov/pubmed/32609721
http://dx.doi.org/10.1371/journal.pgen.1008828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360064/
https://www.ncbi.nlm.nih.gov/pubmed/32609721
http://dx.doi.org/10.1371/journal.pgen.1008828

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