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Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication
Homologous recombination (HR) has an intimate relationship with genome replication, both during repair of DNA lesions that might prevent DNA synthesis and in tackling stalls to the replication fork. Recent studies led us to ask if HR might have a more central role in replicating the genome of Leishm...
Autores principales: | Damasceno, Jeziel D., Reis-Cunha, João, Crouch, Kathryn, Beraldi, Dario, Lapsley, Craig, Tosi, Luiz R. O., Bartholomeu, Daniella, McCulloch, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360064/ https://www.ncbi.nlm.nih.gov/pubmed/32609721 http://dx.doi.org/10.1371/journal.pgen.1008828 |
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