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Golgi compartments enable controlled biomolecular assembly using promiscuous enzymes

The synthesis of eukaryotic glycans – branched sugar oligomers attached to cell-surface proteins and lipids – is organized like a factory assembly line. Specific enzymes within successive compartments of the Golgi apparatus determine where new monomer building blocks are linked to the growing oligom...

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Detalles Bibliográficos
Autores principales: Jaiman, Anjali, Thattai, Mukund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360365/
https://www.ncbi.nlm.nih.gov/pubmed/32597757
http://dx.doi.org/10.7554/eLife.49573