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Golgi compartments enable controlled biomolecular assembly using promiscuous enzymes
The synthesis of eukaryotic glycans – branched sugar oligomers attached to cell-surface proteins and lipids – is organized like a factory assembly line. Specific enzymes within successive compartments of the Golgi apparatus determine where new monomer building blocks are linked to the growing oligom...
Autores principales: | Jaiman, Anjali, Thattai, Mukund |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360365/ https://www.ncbi.nlm.nih.gov/pubmed/32597757 http://dx.doi.org/10.7554/eLife.49573 |
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