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Sonic Hedgehog Signaling Contributes to Chronic Post-Thoracotomy Pain via Activating BDNF/TrkB Pathway in Rats

PURPOSE: Some patients undergoing thoracotomy may suffer from chronic post-thoracotomy pain (CPTP). Treatment of CPTP has been a clinical challenge and the underlying mechanisms of CPTP remain elusive. Recently, sonic hedgehog (Shh) signaling has been shown to be associated with various pain states...

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Detalles Bibliográficos
Autores principales: Yang, Yitian, Wang, Xiaoyan, Zhang, Xuan, You, Shaohua, Feng, Long, Zhang, Yunliang, Shi, Yizheng, Xu, Yuhai, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360429/
https://www.ncbi.nlm.nih.gov/pubmed/32765048
http://dx.doi.org/10.2147/JPR.S245515