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In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells
Microtubules (MTs) mediate mitosis, directional signaling, and are therapeutic targets in cancer. Yet in vivo analysis of cancer cell MT behavior within the tumor microenvironment remains challenging. Here we developed an imaging pipeline using plus-end tip tracking and intravital microscopy to quan...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360550/ https://www.ncbi.nlm.nih.gov/pubmed/32665556 http://dx.doi.org/10.1038/s41467-020-17147-y |