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Region-specific mechanisms of corticosteroid-mediated inotropy in rat cardiomyocytes
Regional differences in ion channel activity in the heart control the sequence of repolarization and may contribute to differences in contraction. Corticosteroids such as aldosterone or corticosterone increase the L-type Ca(2+) current (I(CaL)) in the heart via the mineralocorticoid receptor (MR). H...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360564/ https://www.ncbi.nlm.nih.gov/pubmed/32665640 http://dx.doi.org/10.1038/s41598-020-68308-4 |