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Hypoxic microenvironment shapes HIV-1 replication and latency

Viral replication is defined by the cellular microenvironment and one key factor is local oxygen tension, where hypoxia inducible factors (HIFs) regulate the cellular response to oxygen. Human immunodeficiency virus (HIV) infected cells within secondary lymphoid tissues exist in a low-oxygen or hypo...

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Detalles Bibliográficos
Autores principales: Zhuang, Xiaodong, Pedroza-Pacheco, Isabela, Nawroth, Isabel, Kliszczak, Anna E., Magri, Andrea, Paes, Wayne, Rubio, Claudia Orbegozo, Yang, Hongbing, Ashcroft, Margaret, Mole, David, Balfe, Peter, Borrow, Persephone, McKeating, Jane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360605/
https://www.ncbi.nlm.nih.gov/pubmed/32665623
http://dx.doi.org/10.1038/s42003-020-1103-1