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Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression

Ketohexokinase (KHK) is the first and rate-limiting enzyme of fructose metabolism. Expression of the two alternatively spliced KHK isoforms, KHK-A and KHK-C, is tissue-specific and KHK-C is predominantly expressed in liver, kidney and intestine and responsible for the fructose-catabolizing function....

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Detalles Bibliográficos
Autores principales: Eberhart, Tanja, Schönenberger, Miriam J., Walter, Katharina M., Charles, Khanichi N., Faust, Phyllis L., Kovacs, Werner J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360681/
https://www.ncbi.nlm.nih.gov/pubmed/32733884
http://dx.doi.org/10.3389/fcell.2020.00566