On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges?

Metastasis is the leading cause of death for cancer patients. During cancer progression, the initial detachment of cells from the primary tumor and the later colonization of a secondary organ are characterized as limiting steps for metastasis. Epithelial-mesenchymal transition (EMT) and mesenchymal-...

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Detalles Bibliográficos
Autores principales: Teixeira, Adilson Fonseca, ten Dijke, Peter, Zhu, Hong-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360684/
https://www.ncbi.nlm.nih.gov/pubmed/32733895
http://dx.doi.org/10.3389/fcell.2020.00605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360684/
https://www.ncbi.nlm.nih.gov/pubmed/32733895
http://dx.doi.org/10.3389/fcell.2020.00605

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