Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia

Acute myeloid leukemia (AML) is characterised by a series of genetic and epigenetic alterations that result in deregulation of transcriptional networks. One understudied source of transcriptional regulators are transposable elements (TEs), whose aberrant usage could contribute to oncogenic transcrip...

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Detalles Bibliográficos
Autores principales: Deniz, Özgen, Ahmed, Mamataz, Todd, Christopher D., Rio-Machin, Ana, Dawson, Mark A., Branco, Miguel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360734/
https://www.ncbi.nlm.nih.gov/pubmed/32665538
http://dx.doi.org/10.1038/s41467-020-17206-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360734/
https://www.ncbi.nlm.nih.gov/pubmed/32665538
http://dx.doi.org/10.1038/s41467-020-17206-4

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