CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells

Regulatory T cells (Tregs) are critical mediators of immune homeostasis. The co-stimulatory molecule CD27 is a marker of highly suppressive Tregs, although the role of the CD27-CD70 receptor-ligand interaction in Tregs is not clear. Here we show that after prolonged in vitro stimulation, a significa...

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Detalles Bibliográficos
Autores principales: Arroyo Hornero, Rebeca, Georgiadis, Christos, Hua, Peng, Trzupek, Dominik, He, Li-Zhen, Qasim, Waseem, Todd, John A., Ferreira, Ricardo C., Wood, Kathryn J., Issa, Fadi, Hester, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360768/
https://www.ncbi.nlm.nih.gov/pubmed/32665635
http://dx.doi.org/10.1038/s42003-020-1097-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360768/
https://www.ncbi.nlm.nih.gov/pubmed/32665635
http://dx.doi.org/10.1038/s42003-020-1097-8

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