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Analysis of compositions of microbiomes with bias correction

Differential abundance (DA) analysis of microbiome data continues to be a challenging problem due to the complexity of the data. In this article we define the notion of “sampling fraction” and demonstrate a major hurdle in performing DA analysis of microbiome data is the bias introduced by differenc...

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Detalles Bibliográficos
Autores principales: Lin, Huang, Peddada, Shyamal Das
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360769/
https://www.ncbi.nlm.nih.gov/pubmed/32665548
http://dx.doi.org/10.1038/s41467-020-17041-7