ATM-associated signalling triggers the unfolded protein response and cell death in response to stress

Endoplasmic reticulum (ER) stress can be caused by perturbations in ER function resulting from the accumulation of unfolded/misfolded proteins in the ER lumen. Accumulating unfolded proteins trigger unfolded protein responses (UPRs) through activating three transmembrane sensors on the ER: IRE1α, PE...

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Detalles Bibliográficos
Autores principales: Hotokezaka, Yuka, Katayama, Ikuo, Nakamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360780/
https://www.ncbi.nlm.nih.gov/pubmed/32665601
http://dx.doi.org/10.1038/s42003-020-1102-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360780/
https://www.ncbi.nlm.nih.gov/pubmed/32665601
http://dx.doi.org/10.1038/s42003-020-1102-2

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